Comparative Analysis of Trophoblasts and Angiogenesis in Human Placental Compartments

Trophoblasts perform different functions depending on their location. This study aimed to obtain structural clues about the of villous and extravillous trophoblasts by using light electron microscopy. Term placenta samples were obtained from 10 healthy pregnant women following cesarean sections. Frozen sections stained with hematoxylin-eosin, semi- thin toluidine blue examined a microscope, while contrasted uranyl acetate-lead citrate evaluated under an microscope. Fine features overlapped some stromal cells. In addition usual appearance mature capillaries in stroma, we demonstrated reported maturational stages angiogenetic sprouts term placenta. Extravillous classified according location: fibrinoid, chorion, trophoblastic, column, maternal vascular endothelium, or decidua. All these shared ultrastructural but also distinct each other. decidua, it was noted that endothelial lining vessels invaded few endovascular irregular microvilli. These cells properties both Examination showed angiogenesis still present placentas trophoblasts, have very similar ultrastructurally, suggesting they represent transformational forms.